Spreading of an anchorage-dependent cell on a selectively ligand-coated substrate mediated by receptor-ligand binding.

Abstract

A continuum model was proposed to simulate a biological cell adhering to a substrate surface domain with selectively coated ligands. Cell adhesion was modeled by a traction-separation law depending on the receptor-ligand distance and their densities. It was found that the obtained spreading patterns are consistent with published experimental data and that… (More)
DOI: 10.1002/jbm.a.32258

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