Spread and distribution of drug resistance and compensatory mutations in Plasmodium falciparum

@inproceedings{Dalmau2012SpreadAD,
  title={Spread and distribution of drug resistance and compensatory mutations in Plasmodium falciparum},
  author={Jovel Qui{\~n}onez Dalmau and Irina Tatiana},
  year={2012}
}
In 2010 there were an estimated 216 million cases of malaria worldwide. In Honduras there were ~9000 cases of which 88% were due to Plasmodium vivax mono-infection. Chloroquine (CQ) resistant Plasmodium falciparum have spread throughout the world curtailing its use. The only exception appears to be north of Panama where CQ reportedly remains efficacious and the drug of choice for treating both P. falciparum and P. vivax. Resistance to antimalarials is associated with specific genetic… CONTINUE READING

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