Sporadic inclusion body myositis: phenotypic variability and influence of HLA-DR3 in a cohort of 57 Australian cases.

@article{Needham2008SporadicIB,
  title={Sporadic inclusion body myositis: phenotypic variability and influence of HLA-DR3 in a cohort of 57 Australian cases.},
  author={Merrilee Needham and I. U. James and Alastair J. Corbett and Theresa A. Day and Frank T. Christiansen and Barratt Phillips and F. Mastaglia},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2008},
  volume={79 9},
  pages={
          1056-60
        }
}
  • Merrilee Needham, I. U. James, +4 authors F. Mastaglia
  • Published in
    Journal of neurology…
    2008
  • Medicine
  • BACKGROUND AND AIMS There have been few studies of the variability in the clinical phenotype in sporadic inclusion body myositis (sIBM) and it is not known whether the human leucocyte antigen (HLA) haplotype influences the phenotype and course of the disease. We studied a large cohort of patients with sIBM in order to determine the degree of phenotypic variability and different modes of presentation, as well as the influence of HLA haplotypes. METHOD A cross-sectional study of 57 biopsy… CONTINUE READING

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