Sporadic Creutzfeldt–Jakob disease without dementia at onset: clinical features, laboratory tests and sequential diffusion MRI (in an autopsy–proven case)


A rapidly progressing dementia, followed by focal neurological signs, and evidence of periodic sharp wave complexes (PSWC) in the EEG may lead to the clinical suspicion of Creutzfeldt–Jakob disease (CJD). Different clinical variants of CJD have been described in the past, with prominent extrapyramidal or occipital lobe involvement, all included in the… (More)
DOI: 10.1007/s10072-004-0328-y

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