Spontaneously active cells isolated from the sino-atrial and atrio-ventricular nodes of the rabbit heart.

@article{Taniguchi1981SpontaneouslyAC,
  title={Spontaneously active cells isolated from the sino-atrial and atrio-ventricular nodes of the rabbit heart.},
  author={Junichi Taniguchi and Shinichiro Kokubun and Akinori Noma and Hiroshi Irisawa},
  journal={The Japanese journal of physiology},
  year={1981},
  volume={31 4},
  pages={547-58}
}
Single cells or cell clusters composed of 3-10 cells were isolated from the S-A and A-V nodes of the rabbit heart by coronary perfusion of collagenase dissolved in Ca-free Tyrode solution (0.04%, for 1 hr). For comparison, atrial and ventricular cells were also isolated from the same heart. Shapes of the isolated nodal cell were either rod or round and nodal cells were slightly smaller than ventricular cells. Spontaneous activity was observed in both rod and round nodal cells. The action… CONTINUE READING

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