Spontaneously Occurring Tumors of Companion Animals as Models for Human Cancer

@article{Vail2000SpontaneouslyOT,
  title={Spontaneously Occurring Tumors of Companion Animals as Models for Human Cancer},
  author={D. Vail and E. Macewen},
  journal={Cancer Investigation},
  year={2000},
  volume={18},
  pages={781 - 792}
}
Spontaneous tumors in companion animals (dog and cat) offer a unique opportunity as models for human cancer biology and translational cancer therapeutics. The relatively high incidence of some cancers, similar biologic behavior, large body size, comparable responses to cytotoxic agents, and shorter overall lifespan are the factors that contribute to the advantages of the companion animal model. The tumor types that offer the best comparative interest include lymphoma/leukemia, osteosarcoma, STS… Expand
Canine tumors: a spontaneous animal model of human carcinogenesis.
Translation of new cancer treatments from pet dogs to humans
Spontaneous and genetically engineered animal models; use in preclinical cancer drug development.
The importance of comparative oncology in translational medicine
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 162 REFERENCES
Prognostic factors in feline mammary carcinoma.
Distribution of the hypoxia marker CCI-103F in canine tumors.
The relationship between proliferative and oxygenation status in spontaneous canine tumors.
Comparative aspects of osteosarcoma. Dog versus man.
Prognostic factors for feline mammary tumors.
...
1
2
3
4
5
...