Spontaneously Occurring Tumors of Companion Animals as Models for Human Cancer

  title={Spontaneously Occurring Tumors of Companion Animals as Models for Human Cancer},
  author={David M. Vail and E. Gregory Macewen},
  journal={Cancer Investigation},
  pages={781 - 792}
Spontaneous tumors in companion animals (dog and cat) offer a unique opportunity as models for human cancer biology and translational cancer therapeutics. The relatively high incidence of some cancers, similar biologic behavior, large body size, comparable responses to cytotoxic agents, and shorter overall lifespan are the factors that contribute to the advantages of the companion animal model. The tumor types that offer the best comparative interest include lymphoma/leukemia, osteosarcoma, STS… 

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