[Spontaneous tumors in aged SD-JCL rats (author's transl)].


Incidence of spontaneous tumors was examined in 77 male and 73 female SD-JCL rats reared throughout their lifespan of 5 to 36 months. Total tumor incidences were 60% and 95% for males and females, respectively. The sex difference was mostly attributable to a high incidence of mammary tumor in females. The pituitary tumor was found in 30% of males and 66% of females aged 5 to 36 months while islet cell tumor of the pancreas and thyroid tumor occurred later and the incidence of latter was particularly high in rats lived more than 2 years. Myeloid leukemia appeared to occur as early as 5 months of age.

Cite this paper

@article{Muraoka1977SpontaneousTI, title={[Spontaneous tumors in aged SD-JCL rats (author's transl)].}, author={Yuki Muraoka and Mitsuyasu Itoh and Fumihiko Yamashita and Yuichiro Hayashi}, journal={Jikken dobutsu. Experimental animals}, year={1977}, volume={26 1}, pages={13-22} }