Spontaneous subclinical hypothyroidism in patients older than 55 years: an analysis of natural course and risk factors for the development of overt thyroid failure.

@article{Diez2004SpontaneousSH,
  title={Spontaneous subclinical hypothyroidism in patients older than 55 years: an analysis of natural course and risk factors for the development of overt thyroid failure.},
  author={Juan Jos{\'e} Rodrı́guez Diez and Pedro Iglesias},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2004},
  volume={89 10},
  pages={4890-7}
}
We aimed to analyze the natural course of subclinical hypothyroidism, quantify the incidence rate of overt hypothyroidism, and evaluate the risk factors for the development of definitive thyroid failure in elderly patients. One hundred seven patients (93 women and 14 men) over age 55 yr with subclinical hypothyroidism and no previous history of thyroid disease were prospectively studied. Subjects were followed up for 6-72 months (mean, 31.7 months) with repeated determinations of TSH and free T… CONTINUE READING

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