Spontaneous single-channel activity of neuronal TRP5 channel recombinantly expressed in HEK293 cells.

@article{Yamada2000SpontaneousSA,
  title={Spontaneous single-channel activity of neuronal TRP5 channel recombinantly expressed in HEK293 cells.},
  author={Hiroshi Y Yamada and Minoru Wakamori and Yoko Hara and Yoshihiro Takahashi and Kumiko Konishi and Keiji Imoto and Yasuo Mori},
  journal={Neuroscience letters},
  year={2000},
  volume={285 2},
  pages={111-4}
}
Mammalian homologues of the Drosophila transient receptor potential (trp) protein (TRP) form Ca(2+) permeable cation channels activated in response to stimulation of G-protein-coupled receptors. Establishing biophysical characteristics of basal TRP activity is of great importance in understanding modulatory processes, which underlie enhancement of TRP activity via receptor stimulation. We have examined spontaneous activity of the TRP5 channel recombinantly expressed in human embryonic kidney… CONTINUE READING

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