Spontaneous reporting of serious cutaneous reactions with protein kinase inhibitors

  title={Spontaneous reporting of serious cutaneous reactions with protein kinase inhibitors},
  author={Emmanuelle Faye and Emmanuelle Bondon-Guitton and Pascale Olivier-Abbal and J. -L. Montastruc},
  journal={European Journal of Clinical Pharmacology},
Our aim was to describe all serious cutaneous adverse drug reactions (ADRs) spontaneously reported in France for all oral protein kinase inhibitors, their characteristics and whether they were labeled (reported in the Summary of Product Characteristics) or not. We performed a retrospective observational study in the French PharmacoVigilance Database, selecting for analysis serious cutaneous reactions of patients due to treatment with oral protein kinase inhibitors (erlotinib, gefitinib… CONTINUE READING
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