Corpus ID: 1868429

Spontaneous release of DNA by human blood lymphocytes as shown in an in vitro system.

@article{Anker1975SpontaneousRO,
  title={Spontaneous release of DNA by human blood lymphocytes as shown in an in vitro system.},
  author={P. Anker and M. Stroun and P. Maurice},
  journal={Cancer research},
  year={1975},
  volume={35 9},
  pages={
          2375-82
        }
}
Human blood lymphocytes released DNA in vitro in the absence of any stimulation. Once purified from the complex appearing in the supernatant, this DNA exhibited typical characteristics as shown by its UV absorption curve, its deoxyribose coloration, and its sensitivity to DNase. Elution patterns on hydroxyapatite columns indicated that the excreted DNA is double stranded. The released DNA was smaller than the cellular DNA; its molecular weight ranged from 3.5 x 10(5) to 3.7 x 10(6) daltons. The… Expand
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