Spontaneous regression of highly immunogenic Molluscum contagiosum virus (MCV)-induced skin lesions is associated with plasmacytoid dendritic cells and IFN-DC infiltration.

@article{Vermi2011SpontaneousRO,
  title={Spontaneous regression of highly immunogenic Molluscum contagiosum virus (MCV)-induced skin lesions is associated with plasmacytoid dendritic cells and IFN-DC infiltration.},
  author={William Vermi and Simona Fisogni and Laura Salogni and Leo Schaerer and Heinz Kutzner and Silvano Sozzani and Silvia Lonardi and Cristina Rossini and Piergiacomo Calzavara-Pinton and Philip E. Leboit and Fabio F. Facchetti},
  journal={The Journal of investigative dermatology},
  year={2011},
  volume={131 2},
  pages={426-34}
}
Molluscum contagiosum virus (MCV) infection induces self-limiting cutaneous lesions in an immunocompetent host that can undergo spontaneous regression preceded by local inflammation. On histology, a large majority of MCV-induced lesions are characterized by islands of hyperplastic epithelium containing infected keratinocytes and surrounded by scarce inflammatory infiltrate. However, spontaneous regression has been associated with the occurrence of a dense inflammatory reaction. By histology and… CONTINUE READING
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