Spontaneous regression: a hidden treasure buried in time.

  title={Spontaneous regression: a hidden treasure buried in time.},
  author={Stephen A Hoption Cann and Johannes Pieter van Netten and Christiaan van Netten and Drew W Glover},
  journal={Medical hypotheses},
  volume={58 2},
Spontaneous tumor regression is a phenomenon that has been observed for hundreds, if not thousands of years. Although the term spontaneous implies 'without apparent cause', a review of case reports over the last several hundred years demonstrates that regression generally coincides with acute infections. Observations of this non-specific effect led to the emergence of active cancer immunotherapies by the 1700s. By the 1890s, William Coley refined this approach with a bacterial vaccine which… CONTINUE READING

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