Spontaneous pneumomediastinum in patients with severe acute respiratory syndrome

@article{Chu2004SpontaneousPI,
  title={Spontaneous pneumomediastinum in patients with severe acute respiratory syndrome},
  author={Chung-Ming Chu and Y Y Leung and Joyce Yee-Hing Hui and I. F. N. Hung and Veronica lee Chan and Wah Shing Leung and Kin Ip Law and C. Stanley Chan and K. S. Chan and Kwok Yung Yuen},
  journal={European Respiratory Journal},
  year={2004},
  volume={23},
  pages={802 - 804}
}
Spontaneous pneumomediastinum (SP) unrelated to assisted ventilation is a newly recognised complication of severe acute respiratory syndrome (SARS). The objective of the present study was to examine the incidence, risk factors and the outcomes of SP in a cohort of SARS victims from a community outbreak. Data were retrieved from a prospectively collected database of virologically confirmed SARS patients. One hundred and twelve cases were analysable, with 13 patients developing SP (11.6%) at a… 
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Highly Influential Citations
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102 Citations

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Citation Type

Spontaneous pneumomediastinum in an elderly COVID-19 patient: A case report
TLDR
It is presumed that aging lung changes and bronchopulmonary infection play an important part in the onset of SPM in COVID-19, but severe acute respiratory syndrome may represent a separate pathophysiologic mechanism for pneumomediastinum.
Spontaneous Pneumomediastinum: A Possible Severe Condition in SARS-CoV-2 Pneumonia
TLDR
It remains unclear if SP in SARS-CoV-2 pneumonia is a potential predictor of disease worsening, for it does not seem to be related with a higher rate of mortality.
Air Should Not be There: A Case of Pneumomediastinum and Pneumopericardium in COVID-19
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A 68-year-old Hispanic male with hypertension and gastroesophageal reflux disease, presented with two weeks history of fevers, chills, cough, and progressive shortness of breath was found to be positive for the novel SARS-CoV-2 and his CT of his thorax demonstrated bilateral ground-glass opacities and bilateral reticulations consistent with intraparenchymal injuries.
Pneumomediastinum in COVID-19 disease: Outcomes and relation to the Macklin effect
TLDR
PM incidence is probably increased in the severe acute respiratory syndrome caused by COVID-19, especially in those with greater involvement of the lungs, and the Macklin effect may be an important underlying mechanism of this complication.
Spontaneous pneumomediastinum as a complication of a COVID-19 related pneumonia: case report and review of literature
Pneumomediastinum in COVID-19: Merely a Matter of Lung Frailty?
TLDR
In the absence of a definitive description concluding the development of pneumomediastinum in COVID-19 due to positive pressure ventilation thus far, natural questions arise regarding the aetiology of the complication.
Serious complications in COVID-19 ARDS cases: pneumothorax, pneumomediastinum, subcutaneous emphysema and haemothorax
TLDR
The contribution of MV to alveolar injury caused by infection in COVID-19 ARDS patients may cause more frequent barotrauma compared to classic ARDS and this situation significantly increases the MV and intensive care admission durations of patients.
Spontaneous pneumomediastinum in COVID-19 pneumonia.
TLDR
It is concluded that spontaneous pneumomediastinum is a possible complication of severe COVID-19 pneumonia that can affect patient management and clinical outcomes.
Spontaneous Pneumomediastinum/Pneumothorax in Patients With COVID-19
TLDR
It is presumed that acute lung injury leading to SARS-CoV-2 with associated acute respiratory distress syndrome (ARDS) predisposes patients to this rare complication.
Spontaneous pneumomediastinum and COVID-19 pneumonia: Report of three cases with emphasis on CT imaging
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