Spontaneous oscillation and mechanically induced calcium waves in chondrocytes.

  title={Spontaneous oscillation and mechanically induced calcium waves in chondrocytes.},
  author={Taisuke Kono and Tetsuya Nishikori and H. Kataoka and Yuji Uchio and Mitsuo Ochi and Koh-ichi Enomoto},
  journal={Cell biochemistry and function},
  volume={24 2},
The characteristics of spontaneous calcium (Ca(2+)) oscillation and mechanically induced Ca(2+) waves in articular chondrocytes were studied. In some, but not all, chondrocytes in sliced cartilage and primary cultures, we observed spontaneous oscillation of intracellular Ca(2+) that never spread to adjacent cells. In contrast, a mechanical stimulus to a single cell by touching with a glass rod induced an increase of intracellular Ca(2+) that spread to neighboring cells in a wave-like manner… CONTINUE READING