Spontaneous necrosis in osteosarcoma.

@article{Springfield1991SpontaneousNI,
  title={Spontaneous necrosis in osteosarcoma.},
  author={Dempsy S Springfield and Marius Schakel and Suzanne S. Spanier},
  journal={Clinical orthopaedics and related research},
  year={1991},
  volume={263},
  pages={
          233-7
        }
}
The percentage of necrosis in a primary osteosarcoma after the patient has received preoperative chemotherapy is prognostic and is usually used to select subsequent chemotherapy. However, the percentage of necrosis that occurs spontaneously, without preoperative chemotherapy, has not been adequately studied. The examination of histologic macrosections of 76 osteosarcomas from patients who had not received preoperative treatment and of 20 patients who had received preoperative chemotherapy… CONTINUE READING
BETA