Spontaneous maturation of follicular oocytes in Rana dybowskii in vitro: seasonal influences, progesterone production and involvement of cAMP.

@article{Kwon1989SpontaneousMO,
  title={Spontaneous maturation of follicular oocytes in Rana dybowskii in vitro: seasonal influences, progesterone production and involvement of cAMP.},
  author={Hyuk Bang Kwon and Yon Kuei Lim and Min Ji Choi and Ryun Sup Ahn},
  journal={The Journal of experimental zoology},
  year={1989},
  volume={252 2},
  pages={190-9}
}
Seasonal and hormonal influences regulating oocyte maturation (germinal vesicle breakdown, GVBD) in ovarian follicles of Rana dybowskii were investigated. During the early winter (Dec.-Jan.) GVBD occurred at a low incidence following in vitro culture of intact follicles. Addition of progesterone of frog pituitary homogenate (FPH) to such follicles induced oocyte maturation, whereas IBMX or forskolin inhibited hormone-induced oocyte maturation. The time course of spontaneous in vitro maturation… CONTINUE READING

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