Spontaneous hypoglycemia: diagnostic evaluation and management

@article{Kandaswamy2016SpontaneousHD,
  title={Spontaneous hypoglycemia: diagnostic evaluation and management},
  author={Leelavathy Kandaswamy and Rajeev Raghavan and Joseph M Pappachan},
  journal={Endocrine},
  year={2016},
  volume={53},
  pages={47-57}
}
Spontaneous hypoglycemia is a puzzling clinical problem and an important reason for referral to endocrinologists. Several clinical conditions such as insulinomas, non-insulinoma pancreatogenous hypoglycemia syndrome, insulin autoimmune syndrome, postprandial hypoglycemia (reactive hypoglycemia), non-islet cell tumor hypoglycemia, primary adrenal insufficiency, hypopituitarism, and critical illness can be associated with spontaneous hypoglycemia. Rarely, in patients with mental health issues… 
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[Reactive hypoglycemia - an interdisciplinary approach of the disease of XXI Century].
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Existing knowledge about reactive hypoglycemia - etiology, diagnostic model and treatment is summarized to summarize.
Tumour-induced hypoglycaemia: a narrative review
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There are two main groups of TIH: insulinoma and non-islet cell tumours (NICTs), and accurate diagnosis of Insulinoma versus NICTs provides a rationale for effective and individually tailored management.
Insulin-induced autoimmune syndrome: A case report.
TLDR
In patients with repeated hypoglycemia, IAS should be considered in the differential diagnosis, and Prednisone may be effective for the treatment of hyp glucosecemia in patients with IAS.
Non-Islet Cell Tumor Hypoglycemia Caused by Recurrent Pelvic Solitary Fibrous Tumor
TLDR
Non-islet cell tumor hypoglycemia should be considered in the differential diagnosis of patients presenting with tumors and recurrent hypoglycaemia, especially in patients with a history of ovarian solitary fibrous tumor.
Nutritional guidelines for the management of insulin resistance.
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The aim of this article is to present the most common IR states, namely obesity and Polycystic Ovary Syndrome, and provide nutritional advice to manage IR, hyperinsulinemia, and reactive hypoglycemia that could prevent progression or worsening of IR with resultant beta-cell failure and, as a result, T2D.
The management of neuroendocrine tumours: A nutritional viewpoint
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The aim of this review is to provide dietary advices for each specific condition in patients with NETs, underlining the importance of a nutritional approach to treat malnutrition in this setting.
Hypoglycemia secondary to insulinoma masking the onset of type 1 diabetes in an adolescent
Type 1 diabetes and insulinoma can co‐occur in pediatric patients and may present with episodes of hypo‐ and hyperglycemia, significant glycemic variability, and weight gain. Surgical resection leads…
Continuous Glucose Monitoring in Patients With Insulinoma Treated by Endoscopic Ultrasound-Guided Ethanol Injection
TLDR
Investigation of the continuous glucose monitoring profiles of patients with insulinoma before and after treatment with endoscopic ultrasound–guided ethanol injection found that CGM is useful for detecting hypoglycemia and evaluating curative effect, but the correction of fingertipBlood glucose is necessary when the blood glucose is relatively low.
Pancreatic neuroendocrine tumors: contemporary diagnosis and management
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This manuscript will review pancreatic neuroendocrine tumor subtypes, syndromes, diagnosis, and clinical management.
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