Spontaneous glial calcium waves in the retina develop over early adulthood.

  title={Spontaneous glial calcium waves in the retina develop over early adulthood.},
  author={Zeb L. Kurth-Nelson and Anusha Mishra and Eric A Newman},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={29 36},
Intercellular glial Ca(2+) waves constitute a signaling pathway between glial cells. Artificial stimuli have previously been used to evoke these waves, and their physiological significance has been questioned. We report here that Ca(2+) waves occur spontaneously in rat retinal glial cells, both in the isolated retina and in vivo. These spontaneous waves are propagated by ATP release. In the isolated retina, suramin (P2 receptor antagonist) reduces the frequency of spontaneous wave generation by… CONTINUE READING
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