Spontaneous firing and evoked pauses in the tonically active cholinergic interneurons of the striatum

  title={Spontaneous firing and evoked pauses in the tonically active cholinergic interneurons of the striatum},
  author={J. Goldberg and J. Reynolds},
  • J. Goldberg, J. Reynolds
  • Published 2011
  • Psychology, Medicine
  • Neuroscience
  • The tonically active neurons (TANs) are a population of neurons scattered sparsely throughout the striatum that show intriguing patterns of firing activity during reinforcement learning. Following repeated pairings of a neutral stimulus with a primary reward, TANs develop a transient cessation of firing activity in response to the stimulus, termed the "conditioned pause response." In tasks where specific cues are arranged to signal the probability of particular outcomes, the pause response to… CONTINUE READING
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