Spontaneous disappearance of high titre factor VIII inhibitor 15 years after unsuccessful ITI.

@article{Thom2009SpontaneousDO,
  title={Spontaneous disappearance of high titre factor VIII inhibitor 15 years after unsuccessful ITI.},
  author={K E Thom and Christoph Male and Jutta C Falger and Ingrid Pabinger},
  journal={Hamostaseologie},
  year={2009},
  volume={29 2},
  pages={149-50}
}
The most serious complication of haemophilia A is development of a high-titre factor VIII (FVIII) inhibitor which renders the patient unresponsive to FVIII replacement. Bleeding complications can only be controlled using FVIII-inhibitor bypassing agents but their effect is less certain. The ultimate goal is to eliminate the inhibitor by immune tolerance… CONTINUE READING