Spontaneous deletion formation within the beta-galactosidase gene of Lactobacillus bulgaricus.

@article{Mollet1990SpontaneousDF,
  title={Spontaneous deletion formation within the beta-galactosidase gene of Lactobacillus bulgaricus.},
  author={Beat Mollet and Mich{\`e}le Delley},
  journal={Journal of bacteriology},
  year={1990},
  volume={172 10},
  pages={5670-6}
}
To investigate the genetic stability of the dairy organism Lactobacillus bulgaricus, we have analyzed 107 spontaneous mutations of the beta-galactosidase gene of this organism. Ten of these mutations were DNA rearrangements giving rise to different deletions, located predominantly within a small hot spot area. The DNA sequences of the different deletion junctions have been determined. The analysis showed that the deletions can be divided into two classes, depending on the presence of short… CONTINUE READING

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