Spontaneous breathing affects the spatial ventilation and perfusion distribution during mechanical ventilatory support.

@article{Neumann2005SpontaneousBA,
  title={Spontaneous breathing affects the spatial ventilation and perfusion distribution during mechanical ventilatory support.},
  author={Peter Neumann and Hermann Wrigge and Joerg Zinserling and Jose Hinz and Enn Maripuu and Lars Goran Andersson and Christian Putensen and G{\"o}ran Hedenstierna},
  journal={Critical care medicine},
  year={2005},
  volume={33 5},
  pages={1090-5}
}
OBJECTIVE In acute respiratory failure, gas exchange improves with spontaneous breathing during airway pressure release ventilation (APRV). The mechanisms for this improvement are not fully clear. We have shown that APRV with spontaneous breathing reopens nonaerated lung tissue in dorsal juxtadiaphragmatic regions. We hypothesized that spontaneous breathing… CONTINUE READING