Spontaneous basophil responses in food-allergic children are transferable by plasma and are IgE-dependent.

@article{Schroeder2013SpontaneousBR,
  title={Spontaneous basophil responses in food-allergic children are transferable by plasma and are IgE-dependent.},
  author={John T. Schroeder and Anja P. Bieneman and Kristin L. Chichester and Corinne A. Keet and Robert G. Hamilton and Donald W MacGlashan and Robert A. B. Wood and Pamela A. Frischmeyer-Guerrerio},
  journal={The Journal of allergy and clinical immunology},
  year={2013},
  volume={132 6},
  pages={
          1428-31
        }
}
To the Editor: Early studies showed that up to 80% of children with food allergy demonstrate high spontaneous basophil histamine release (SBHR).1 An association with IgE was suggested because basophils from food-allergic (FA) children additionally released histamine to the IgE-dependent histamine-releasing factor.2 However, the exact mechanism(s) responsible for SBHR, including the dependency for IgE, remains poorly understood. We recently reported that SBHR significantly decreased in… Expand
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