Spontaneous and evoked inhibitory junction potentials in the circular muscle layer of mouse colon.

@article{Spencer1998SpontaneousAE,
  title={Spontaneous and evoked inhibitory junction potentials in the circular muscle layer of mouse colon.},
  author={Nick J Spencer and Robert Bywater and Mollie E. Holman and Grahame John Saint Clair Taylor},
  journal={Journal of the autonomic nervous system},
  year={1998},
  volume={69 2-3},
  pages={115-21}
}
Intracellular microelectrodes were used to record spontaneous and evoked inhibitory junction potentials (IJPs) from the circular muscle layer of an in vitro preparation of whole mouse colon. Membrane potential recordings were made from cells of the mid to distal region of colon at 36 +/- 1 degrees C in a modified Krebs' solution that contained atropine (1 microM) and nifedipine (1-2 microM). Spontaneously occurring hyperpolarisations of irregular amplitude and frequency (range: up to 20 mV and… CONTINUE READING
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