Spontaneous activation of light-sensitive channels in Drosophila photoreceptors

@article{Hardie1994SpontaneousAO,
  title={Spontaneous activation of light-sensitive channels in Drosophila photoreceptors},
  author={Roger C. Hardie and Baruch Minke},
  journal={The Journal of General Physiology},
  year={1994},
  volume={103},
  pages={389 - 407}
}
In Drosophila photoreceptors light induces phosphoinositide hydrolysis and activation of Ca(2+)-permeable plasma membrane channels, one class of which is believed to be encoded by the trp gene. We have investigated the properties of the light-sensitive channels under conditions where they are activated independently of the transduction cascade. Whole-cell voltage clamp recordings were made from photoreceptors in a preparation of dissociated Drosophila ommatidia. Within a few minutes of… CONTINUE READING
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