Spontaneous DNA repair in human mononuclear cells is calcium-dependent.


Spontaneous DNA repair in peripheral blood mononuclear cells (PBMC) has been recently described. The aim of this study was to evaluate whether spontaneous DNA repair is Ca(2+)-dependent, as in vitro-stimulated DNA repair. Spontaneous DNA repair in PBMC was measured in a 1mM Ca2+ medium. The effect of extracellular Ca2+ chelation by EGTA, intracellular Ca2… (More)


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@article{Ori2005SpontaneousDR, title={Spontaneous DNA repair in human mononuclear cells is calcium-dependent.}, author={Yaacov Ori and Michal Herman and Avry Chagnac and Tsipora Malachi and Uzi Gafter and Asher Korzets}, journal={Biochemical and biophysical research communications}, year={2005}, volume={336 3}, pages={842-6} }