We provide evidence for the presence of cannabinoid CB2 receptors in some cellular types of the cochlea of the adult albino rat. Cannabinoids and their receptors are increasingly being studied because of their high potential for clinical use. As a hyperspecialized portion of the peripheral nervous system, study of the expression and function of cannabinoid… (More)
Fig 7. Relative quantification of CB2 immunofluorescence labeling intensity in healthy and CDDPtreated animals by ImageJ.Detailed view of the stria vascularis (SV) and the IHC (arrowhead) of healthy (A and C) and CDDP-treated animals (B and D) (Scale bar = 100μm). Relative immunofluorescence in the IHC and in the stria vascularis of healthy and CDDP-treated animals (E). CB2 relative immunofluorescence was significantly higher only in the stria vascularis of animals treated with CDDP if compared with the control group. The diagram include the mean, the standard deviation (n = 6; 3 control and 3 CDDP-treated), and the ANOVA results (difference statistically significant in each cellular structure between healthy and CDDPtreated animals *p<0.05).