Spongiatriol Inhibits Nuclear Factor Kappa B Activation and Induces Apoptosis in Pancreatic Cancer Cells

@inproceedings{Guzmn2013SpongiatriolIN,
  title={Spongiatriol Inhibits Nuclear Factor Kappa B Activation and Induces Apoptosis in Pancreatic Cancer Cells},
  author={Esther Amalia Guzm{\'a}n and Michael Maher and Alexis Temkin and Tara Peterson Pitts and Amy E Wright},
  booktitle={Marine drugs},
  year={2013}
}
Pancreatic cancer, the fourth leading cause of cancer death in the US, is highly resistant to all current chemotherapies, and its growth is facilitated by chronic inflammation. The majority of pro-inflammatory cytokines initiate signaling cascades that converge at the activation of the Nuclear Factor Kappa B (NFκB), a signal transduction molecule that… CONTINUE READING