Spoligotyping of Mycobacterium tuberculosis isolates from Pakistan reveals predominance of Central Asian Strain 1 and Beijing isolates.

@article{Hasan2006SpoligotypingOM,
  title={Spoligotyping of Mycobacterium tuberculosis isolates from Pakistan reveals predominance of Central Asian Strain 1 and Beijing isolates.},
  author={Zahra Hasan and Mahnaz Tanveer and Akbar Kanji and Qaiser Hasan and Solomon Ghebremichael and Rumina Hasan},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 5},
  pages={1763-8}
}
The estimated incidence of tuberculosis in Pakistan is 181 per 100,000; however, there is limited information on Mycobacterium tuberculosis genotypes circulating in the country. We studied 314 M. tuberculosis clinical isolates; of these, 197 (63%) isolates grouped into 22 different clusters, while 119 (37%) had unique spoligotypes. Eighty-nine percent of the isolates were pulmonary (Pul), and 11% were extrapulmonary (E-Pul). We identified Central Asian Strain (CAS), Beijing, T1, Latin American… CONTINUE READING