SplitPocket: identification of protein functional surfaces and characterization of their spatial patterns

Abstract

SplitPocket (http://pocket.uchicago.edu/) is a web server to identify functional surfaces of protein from structure coordinates. Using the Alpha Shape Theory, we previously developed an analytical approach to identify protein functional surfaces by the geometric concept of a split pocket, which is a pocket split by a binding ligand. Our geometric approach… (More)
DOI: 10.1093/nar/gkp308

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