Split hand syndrome in amyotrophic lateral sclerosis: different excitability changes in the thenar and hypothenar motor axons.

@article{Shibuya2013SplitHS,
  title={Split hand syndrome in amyotrophic lateral sclerosis: different excitability changes in the thenar and hypothenar motor axons.},
  author={Kazumoto Shibuya and Sonoko Misawa and Saiko Nasu and Yukari Sekiguchi and Satsuki Mitsuma and M Beppu and Shigeki Ohmori and Yuta Iwai and Shoichi Ito and Kazuaki Kanai and Yasunori Sato and Satoshi Kuwabara},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2013},
  volume={84 9},
  pages={969-72}
}
BACKGROUND In amyotrophic lateral sclerosis (ALS), muscle wasting preferentially affects the abductor pollicis brevis (APB) and first dorsal interosseous over the abductor digit minimi (ADM), and this is termed 'split hand'. Previous axonal excitability studies have suggested increased nodal persistent sodium current and reduced potassium current in motor axons in ALS, but the extent of excitability changes in APB and ADM axons in ALS has never been compared. OBJECTIVE To elucidate the… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…