Split-dose exposures versus dual ion exposure in human cell neoplastic transformation

@article{Bennett2007SplitdoseEV,
  title={Split-dose exposures versus dual ion exposure in human cell neoplastic transformation},
  author={Paula V. Bennett and Noelle C Cutter and Betsy M. Sutherland},
  journal={Radiation and Environmental Biophysics},
  year={2007},
  volume={46},
  pages={119-123}
}
Since radiation fields of space contain many-fold more protons than high atomic number, high energy (HZE) particles, cells in astronaut crews will experience on average several proton hits before an HZE hit. Thus radiation regimes of proton exposure before HZE particle exposure simulate space radiation exposure, and measurement of the frequency of neoplastic transformation of human primary cells to anchorage-independent growth simulates an initial step in cancer induction. Although previous… 
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TLDR
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