Split Samples and Design Sensitivity in Observational Studies

  title={Split Samples and Design Sensitivity in Observational Studies},
  author={Ruth Heller and Paul R. Rosenbaum and Dylan S. Small},
An observational or nonrandomized study of treatment effects may be biased by failure to control for some relevant covariate that was not measured. The design of an observational study is known to strongly affect its sensitivity to biases from covariates that were not observed. For instance, the choice of an outcome to study, or the decision to combine several outcomes in a test for coherence, can materially affect the sensitivity to unobserved biases. Decisions that shape the design are… CONTINUE READING


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