Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants.

@article{Potashkin1989SplicingOT,
  title={Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants.},
  author={Judith A Potashkin and D. A. Frendewey},
  journal={Nucleic acids research},
  year={1989},
  volume={17 19},
  pages={
          7821-31
        }
}
U6 RNA is a member of a class of small abundant stable nuclear RNAs that are essential for splicing. In all species examined so far, the U6 RNA is a RNA polymerase III transcript. The U6 gene of the fission yeast Schizosaccharomyces pombe is unusual in that it is interrupted by an intron whose structure is similar to those found in pre-mRNAs. As part of our previous analysis of three S. pombe temperature sensitive pre-mRNA splicing mutants we examined their spliceosomal snRNA content. In… CONTINUE READING
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