Splicing and 3'-processing of the tyrosine tRNA of Trypanosoma brucei.

  title={Splicing and 3'-processing of the tyrosine tRNA of Trypanosoma brucei.},
  author={Andr{\'e} Schneider and K P McNally and Nina Agabian},
  journal={The Journal of biological chemistry},
  volume={268 29},
Trypanosoma brucei belongs to a family of protozoa that is characterized as having diverged early in the evolution of eukaryotes. Many unusual forms of RNA processing have been discovered in these cells, one of which is trans-splicing, and, although a great number of genes have been sequenced, no evidence for cis-splicing has yet been found. This study shows that tRNA(Tyr) of T. brucei contains an 11-nucleotide intron. tRNA of the size predicted for unspliced precursor was detected by Northern… CONTINUE READING


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