Spliced leader RNA trans-splicing in dinoflagellates.

  title={Spliced leader RNA trans-splicing in dinoflagellates.},
  author={Huan Zhang and Yubo Hou and Lilibeth N. Miranda and David A. Campbell and Nancy R. Sturm and Terry Gaasterland and Senjie Lin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={104 11},
Through the analysis of hundreds of full-length cDNAs from fifteen species representing all major orders of dinoflagellates, we demonstrate that nuclear-encoded mRNAs in all species, from ancestral to derived lineages, are trans-spliced with the addition of the 22-nt conserved spliced leader (SL), DCCGUAGCCAUUUUGGCUCAAG (D = U, A, or G), to the 5' end. SL… CONTINUE READING