Splenic calcifications in heterozygote sickle cell patients


A small, fibrotic, and even calcified spleen is the hallmark of homozygote sickle cell disease in adults. Such a condition is very rare in sickle-thalassemia and, to our knowledge, not previously reported in a sickle cell trait. We report two heterozygote sickle cell siblings with splenic calcifications, one sickle cell trait and one sickle-β+-thalassemia, without any history suggestive of splenic vasooclusive-infarctive crisis.

DOI: 10.1007/s002619900473

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@article{zgen1999SplenicCI, title={Splenic calcifications in heterozygote sickle cell patients}, author={Ali {\"{O}zgen and Deniz Akata and Alev Arat and M{\"{u}rsel {\"{O}zdoğan and O. Akhan and Mustafa Nasuh {\"{O}zmen}, journal={Abdominal Imaging}, year={1999}, volume={24}, pages={188-190} }