Splenectomy protects the kidneys against ischemic reperfusion injury in the rat.

@article{Hiroyoshi2012SplenectomyPT,
  title={Splenectomy protects the kidneys against ischemic reperfusion injury in the rat.},
  author={Toshiya Hiroyoshi and Masahiro Tsuchida and Koichi Uchiyama and Koki Fujikawa and Takahiro Komatsu and Yoshihiro Kanaoka and Hideyasu Matsuyama},
  journal={Transplant immunology},
  year={2012},
  volume={27 1},
  pages={8-11}
}
BACKGROUND Ischemic reperfusion (I/R) injury of the kidney is closely associated with delayed graft function, increased acute rejection, and late allograft dysfunction. Splenectomy reduced hepatic I/R injury by inhibiting leukocyte infiltration in the liver, release of TNF-α, cell apoptosis, and expression of caspase-3. Thus, we investigated the effects of splenectomy on renal I/R injury in the rat. METHODS Male Wistar rats were assigned to four groups: sham operation (sham group), sham… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Tumor Necrosis Factor and Splenectomy

Turkish journal of haematology : official journal of Turkish Society of Haematology • 2016
View 2 Excerpts

Protective role of spleen-derived macrophages in lung inflammation, injury, and fibrosis induced by nitrogen mustard.

American journal of physiology. Lung cellular and molecular physiology • 2015
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 30 references

[Effects of mycophenolate mofetil in ischemic acute renal failure in rats].

Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia • 2007

Similar Papers

Loading similar papers…