Splenectomy in patients with hepatocellular carcinoma and hypersplenism.

  title={Splenectomy in patients with hepatocellular carcinoma and hypersplenism.},
  author={Yasuhiko Sugawara and J Jeremy Yamamoto and Kazuaki Shimada and Susumu Yamasaki and Tomoo Kosuge and Tadatoshi Takayama and Masatoshi Makuuchi},
  journal={Journal of the American College of Surgeons},
  volume={190 4},
BACKGROUND Hypersplenism secondary to portal hypertension is common in hepatocellular carcinoma (HCC), but surgeons still face the unresolved problem of how to manage HCC patients with hypersplenism. STUDY DESIGN The records of 48 patients with HCC and hypersplenism were retrospectively examined and postoperative changes in platelet counts, serum total bilirubin levels, and dinical staging scores were analyzed to evaluate the clinical value of combined splenectomy and liver resection… CONTINUE READING

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