Splenectomy and subsequent mortality in veterans of the 1939-45 war.

@article{Robinette1977SplenectomyAS,
  title={Splenectomy and subsequent mortality in veterans of the 1939-45 war.},
  author={Carole Robinette and Joseph F. Jr. Fraumeni},
  journal={Lancet},
  year={1977},
  volume={2 8029},
  pages={127-9}
}
A long-term follow-up of 740 American servicemen splenectomised because of trauma during the 1939-45 war showed a significant excess mortality from pneumonia and ischaemic heart-disease. Mortality from cirrhosis was also increased, but not significantly. The findings confirm that the risk of fatal infections is increased by asplenia; however, the risk of cancer was not increased, as it is in some other immunodeficiency states. Post-splenectomy thrombocytosis and hypercoagulability may account… CONTINUE READING

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