Spleen necrosis virus, an avian retrovirus, can infect primate cells.

  title={Spleen necrosis virus, an avian retrovirus, can infect primate cells.},
  author={H M Koo and Anthony M. C. Brown and Yacov Ron and Joseph P. Dougherty},
  journal={Journal of virology},
  volume={65 9},
Spleen necrosis virus (SNV) is an avian retrovirus that can infect some mammalian cells such as dog cells as well as all avian cells tested to date. We were interested in testing whether SNV could also infect primate cells. For these experiments, we used HeLa and COS-7 cells. Initially, we determined whether the SNV long terminal repeat promoter was functional in HeLa and COS-7 cells. In transient transfection assays, the SNV promoter efficiently directed chloramphenicol acetyltransferase gene… CONTINUE READING


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