Splanchnic nerve transection abolishes the age-dependent increase of neuropeptide Y-like immunoreactivity in rat adrenal gland.


Using an antiserum directed against porcine neuropeptide Y (NPY), a high concentration of NPY immunoreactivity (NPY-IR) was detected in rat adrenal gland. The level of NPY-IR in the adrenal gland was found to increase considerably with age. Biochemical characterization by reverse-phase HPLC indicated that this increase was due to accumulations of NPY and… (More)