Splanchnic nerve activation inhibits the increase in duodenal HCO3- secretion induced by luminal acidification in the rat.

@article{Jnson1989SplanchnicNA,
  title={Splanchnic nerve activation inhibits the increase in duodenal HCO3- secretion induced by luminal acidification in the rat.},
  author={Claes J{\"o}nson and P Tunb{\"a}ck-Hanson and Lars F{\"a}ndriks},
  journal={Gastroenterology},
  year={1989},
  volume={96 1},
  pages={45-9}
}
Acid exposure of the duodenal mucosa increased duodenal HCO3- secretion by approximately 60%. When the acid exposure was performed simultaneously with an arterial bleeding of 0.6 ml/100 g body wt (10% of the total blood volume), the increase in duodenal HCO3- secretion was totally abolished. When the acid exposure and bleeding procedures were performed at the same time in rats with bilaterally cut splanchnic nerves, alkaline secretion increased by 60%, as it did in the unbled rats. Direct… CONTINUE READING

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