Splanchnic and systemic vasodilation: the experimental models.

  • Reiner Wiest
  • Published 2007 in Journal of clinical gastroenterology


Experimental models are a sine qua non condition for unraveling the specific components and mechanisms contributing to vascular dysfunction and arterial vasodilation in portal hypertension. Moreover, a careful selection of the type of animal model, vascular bed, and methodology is crucial for any investigation of this issue. In this review, some critical… (More)