Spiroscytalin, a new tetramic acid and other metabolites of mixed biogenesis from Scytalidium cuboideum.

@article{SyCordero2015SpiroscytalinAN,
  title={Spiroscytalin, a new tetramic acid and other metabolites of mixed biogenesis from Scytalidium cuboideum.},
  author={Arlene A. Sy-Cordero and M. Figueroa and H. Raja and Maria Elena Meza Avi{\~n}a and Mitchell P Croatt and A. F. Adcock and D. Kroll and M. Wani and C. Pearce and N. Oberlies},
  journal={Tetrahedron},
  year={2015},
  volume={71 47},
  pages={
          8899-904
        }
}
  • Arlene A. Sy-Cordero, M. Figueroa, +7 authors N. Oberlies
  • Published 2015
  • Chemistry, Medicine
  • Tetrahedron
  • Spiroscytalin (1), a new tetramic acid that possesses an uncommon spiro-ring fusion between a polyketide-derived octalin ring system and a 2,4-pyrrolidinedione, along with two known compounds, leporin B (2) and purpactin A (3), were isolated from a solid phase culture of the fungus Scytalidium cuboideum (MSX 68345). The molecular connectivity of 1-3 was determined using NMR spectroscopy and mass spectrometry. The relative configurations of 1 and 2 were determined by NOESY experiments. The… CONTINUE READING
    6 Citations

    Figures, Tables, and Topics from this paper

    Paper Mentions

    References

    SHOWING 1-10 OF 37 REFERENCES
    Coniosetin, a novel tetramic acid antibiotic from Coniochaeta ellipsoidea DSM 13856.
    • 45
    • PDF
    Peptaibols from two unidentified fungi of the order Hypocreales with cytotoxic, antibiotic, and anthelmintic activities
    • 49
    • PDF
    Benzophenones and biflavonoids from Rheedia edulis.
    • 34
    Synthesis of penicillenol C1 and of a bis-azide analogue for photoaffinity labeling.
    • 28
    Leporin B: a novel hexokinase II gene inducing agent from an unidentified fungus.
    • 21