Spironolactone administration and training-induced hypervolemia.


The purpose of this study was to determine the contribution of aldosterone to plasma volume expansion accompanying short-term exercise training. Twelve healthy males (age = 26.5 +/- 5.8) cycled for 120 min on three consecutive days at a relative exercise intensity of 65% VO2max. Half of the subjects were treated with 25 mg of spironolactone taken four times… (More)


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