Spirocurcasone, a diterpenoid with a novel carbon skeleton from Jatropha curcas.

@article{Chianese2011SpirocurcasoneAD,
  title={Spirocurcasone, a diterpenoid with a novel carbon skeleton from Jatropha curcas.},
  author={Giuseppina Chianese and Ernesto Fattorusso and Olapeju O. Aiyelaagbe and Paolo Luciano and Heinz C. Schröder and Werner E. G. M{\"u}ller and Orazio Taglialatela‐Scafati},
  journal={Organic letters},
  year={2011},
  volume={13 2},
  pages={
          316-9
        }
}
Spirocurcasone (14), a diterpenoid possessing the unprecedented "spirorhamnofolane" skeleton, was isolated from the root barks of Jatropha curcas, a plant extensively cultivated throughout the world, along with 11 known and two other new diterpenoids. The stereostructure of spirocurcasone was established using HRESIMS, NMR, and quantum mechanical calculation of the electronic circular dichroic (ECD) spectrum. Some of the isolated diterpenoids showed a potent activity against L5178Y, a mouse… 
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