Spiro[isobenzofuran-1(3H),4'-piperidines]. 3. Diuretic and antihypertensive properties of compounds containing a sulfur attached to nitrogen.

Abstract

The synthesis and antihypertensive and diuretic activity of several N-sulfur derivatives of 3-phenylspiro[isobenzofuran-1(3H),4'-piperidine] are reported. Benzenesulfenamide 3 possessed marked, species-specific diuretic and antihypertensive activity in rats.

Cite this paper

@article{Klioze1978Spiroisobenzofuran13H4piperidines3D, title={Spiro[isobenzofuran-1(3H),4'-piperidines]. 3. Diuretic and antihypertensive properties of compounds containing a sulfur attached to nitrogen.}, author={Solomon S. Klioze and W. J. Novick}, journal={Journal of medicinal chemistry}, year={1978}, volume={21 4}, pages={400-3} }