Spinocerebellar ataxia type 1 (SCA1): new pathoanatomical and clinico-pathological insights.


AIMS Spinocerebellar ataxia type 1 (SCA1) represents the first molecular genetically characterized autosomal dominantly inherited cerebellar ataxia and is assigned to the CAG-repeat or polyglutamine diseases. Owing to limited knowledge about SCA1 neuropathology, appropriate pathoanatomical correlates of a large variety of SCA1 disease symptoms are missing… (More)
DOI: 10.1111/j.1365-2990.2012.01259.x